Intracellular localisation, geno- and cytotoxic response of polyN-isopropylacrylamide (PNIPAM) nanoparticles to human keratinocyte (HaCaT) and colon cells (SW 480)
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چکیده
منابع مشابه
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells.
Mechanisms regulating CYP4F genes remain under investigation, although characterization of CYP4F regulatory modalities would facilitate the discovery of new drug targets. This present study shows that all-trans- and 9-cis-retinoic acids can inhibit CYP4F11 expression in human keratinocyte-derived HaCaT cells. Transrepression of many genes by retinoic acids is mediated by interactions between re...
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متن کاملOcular Biocompatibility of Poly-N-Isopropylacrylamide (pNIPAM)
Purpose. To study the safety of intravitreal injections of poly-N-isopropylacrylamide (pNIPAM) tissue adhesive in rabbit eyes. Methods. Twelve study rabbits received an intravitreal injection of 0.1 mL 50% pNIPAM in the right eye. Follow-up examinations included color fundus photography, fundus fluorescein angiography (FA), optical coherence tomography (OCT), and electroretinography (ERG). Subs...
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ژورنال
عنوان ژورنال: Toxicology Letters
سال: 2010
ISSN: 0378-4274
DOI: 10.1016/j.toxlet.2010.06.011